Forscherprofil
Prof. Dr. rer. nat. Anja Voß-Böhme
Fakultät Informatik/Mathematik | Professur für Mathematik/Operations Research- angewandte Statistik
- Mathematische Modellierung, insbesondere stochastische räumliche dynamische Systeme in der Systembiologie
- Stochastische Prozesse, insbesondere: Stochastische Vielteilchensysteme, Markov-Chain-Monte-Carlo-Methoden, Markovketten, Probabilistische zelluläre Automaten, Diffusionsprozesse
ORCID: 0000-0001-6510-8694
E-Mail: anja.voss-boehme(at)htw-dresden.de
ResearchGate: https://www.researchgate.net/profile/Anja_Voss-Boehme
2Geleitete Drittmittelprojekte
1Mitarbeit in Drittmittelprojekten
25Publikationen
- Modeling collective cell motion: are on- and off-lattice models equivalent?
NAVA-SEDENO, Josue Manik, VOß-BÖHME, Anja, HATZIKIROU, Haralampos, DEUTSCH, Andreas and PERUANI, Fernando, 2020. Modeling collective cell motion: are on- and off-lattice models equivalent?. Philosophical Transactions of the Royal Society B. DOI:10.1098/rstb.2019.0378 - Patterns of Tumor Progression Predict Small and Tissue-Specific Tumor-Originating Niches
BUDER, Thomas, DEUTSCH, Andreas, KLINK, Barbara, VOSS-BÖHME, Anja, 2019. Patterns of Tumor Progression Predict Small and Tissue-Specific Tumor-Originating Niches. In: Evolution and Ecology of Cancer, Wellcome Genome Campus, UK, July 17-19, 2019. - Stem cell-associated heterogeneity in Glioblastoma results from intrinsic tumor plasticity shaped by the microenvironment
DIRKSE, Anne, GOEBIEWSKA, Anna, BUDER, Thomas, NAZAROV, Petr V., MULLER, Arnaud, POOVATHINGAL, Suresh, BRONS, Nicolaas H. C., LEITE, Sonia, SAUVAGEOT, Nicolas, SARKISJAN, Dzjemma, SEYFRIED, Mathieu, FRITAH, Sabrina, STIEBER, Daniel, MICHELUCCI, Alessandro, HERTEL, Frank, HEROLD-MENDE, Christel, AZUAJE, Francisco, SKUPIN, Alexander, BJERKVIG, Rolf, DEUTSCH, Andreas, VOß-Böhme, Anja, NICLOU, Simone P. , 2019. Stem cell-associated heterogeneity in Glioblastoma results from intrinsic tumor plasticity shaped by the microenvironment. Nature Communications 10, Article number: 1787 (2019). DOI: 10.1038/s41467-019-09853-z - Model-driven inference of the cellular mechanisms in the early
phase of tumor development
VOß-BöHME, Anja, 2019. Model-driven inference of the cellular mechanisms in the early phase of tumor development. In: Perspectives in Mathematical Biology, Schellerhau, Jan 31- Feb 2. - Patterns of Tumor Progression Predict Small and Tissue-Specific Tumor-Originating Niches
DEUTSCH, Andreas, KLINK, Barbara, VOß-BöHME, Anja, 2019. Patterns of Tumor Progression Predict Small and Tissue-Specific Tumor-Originating Niches. In: Frontiers in Oncology. 8:668.. DOI: 10.3389/fonc.2018.00668 - Impact of cell migration plasticity on tumor growth and invasion: A cell-based approach
VOß-BöHME, Anja, 2018. Impact of cell migration plasticity on tumor growth and invasion: A cell-based approach. In: 11th European Conference on Mathematical and Theoretical Biology. Lisbon, July 23 –27, 2018. - Cellular automaton models for analyzing the collective
migration of heterogeneous cell populations
VOß-BöHME, Anja, 2018. Cellular automaton models for analyzing the collective migration of heterogeneous cell populations. In: Summer Solstice 2018 Conference on Discrete Models of Complex Systems, Gdansk, June 25-27, 2018. - Analyzing the impact of cell turnover on the plasticity of tissue
polarity patterns by cellular automaton modeling: The dynamically diluted
alignment model
HOFFMANN, Karl B., VOSS-BÖEHME, Anja, RINK, Jochen C., BRUSCH, Lutz, 2018. Analyzing the impact of cell turnover on the plasticity of tissue polarity patterns by cellular automaton modeling: The dynamically diluted alignment model. In: Summer Solstice 2018 Conference on Discrete Models of Complex Systems, Gdansk, June 25-27, 2018. - Cellular Potts models for interacting cell populations: Mathematical foundation, challenges and future prospects.
VOSS-BÖHME, Anja, 2018. Cellular Potts models for interacting cell populations: Mathematical foundation, challenges and future prospects.. In: Pierre-Yves LOUIS, Francesca R. NARDI(eds) Probabilistic Cellular Automata. Emergence, Complexity and Computation, vol 27. Springer, Cham. Online ISBN: 978-3-319-65558-1 Verfügbar unter DOI: 10.1007/978-3-319-65558-1_19 - A Dynamically Diluted Alignment Model Reveals the Impact of Cell Turnover on the Plasticity of Tissue Polarity Patterns
HOFFMANN, Karl B., VOSS-BÖHME, Anja, RINK, Jochen, BRUSCH, Lutz , 2017. A Dynamically Diluted Alignment Model Reveals the Impact of Cell Turnover on the Plasticity of Tissue Polarity Patterns. In: Symposium Engineering Life 2017: Form and Function 19-20 October 2017, Steigenberger Hotel de Sâxe in Dresden. - Collective migration of heterogeneous cell populations
VOß-BöHME, Anja, 2017. Collective migration of heterogeneous cell populations. Zif Workshop 'Multiscale Analysis and Modeling of Collective Migration in Biological Systems', Zentrum für Interdisziplinäre Forschung (ZiF) Bielefeld, 9.-13.10.2017. - A Dynamically Diluted Alignment Model Reveals the Impact of Cell Turnover on the Plasticity of Tissue Polarity Patterns
HOFFMANN, Karl, VOß-BÖHME, Anja, RINK, Jochen C., BRUSCH, Lutz, 2017. A Dynamically Diluted Alignment Model Reveals the Impact of Cell Turnover on the Plasticity of Tissue Polarity Patterns. Journal of the Royal Society Interface 14 (2017) 20170466; doi: 10.1098/rsif.2017.0466. . https://doi.org/10.1098/rsif.2017.0466 - Amoeboid-mesenchymal migration plasticity promotes invasion only in complex heterogeneous microenvironments
TALKENBERGER, Katrin, CALVACANTI-ADAM; Elisabetta Ada, VOSS-BÖHME, Anja, DEUTSCH, Andreas, 2017. Amoeboid-mesenchymal migration plasticity promotes invasion only in complex heterogeneous microenvironments. Scientific Reports 7, Article number: 9237 (2017). Doi: 10.1038/s41598-017-09300-3 - Cell adhesion heterogeneity reinforces tumour cell dissemination: novel insights from a mathematical model
REHER, David, KLINK, Barbara, DEUTSCH, Andreas, VOSS-BÖHME, Anja, 2017. Cell adhesion heterogeneity reinforces tumour cell dissemination: novel insights from a mathematical model. Biology Direct (2017) 12:18. DOI 10.1186/s13062-017-0188-z - CellTrans: An R package to quantify stochastic cell state transitions.
BUDER, Thomas, DEUTSCH, Andreas, SEIFERT, Michael, VOSS-BÖHME, Anja, 2017. CellTrans: An R package to quantify stochastic cell state transitions.. Bioinformatics and Biology Insights 11, 1-14 (2017). DOI:10.1177/1177932217712241 - On the statistical power of Baarda's outlier test and some alternative.
LEHMANN, Rüdiger, VOß-BÖHME, Anja, 2017. On the statistical power of Baarda's outlier test and some alternative.. Journal of Geodetic Science 7 (1), 68-78 (2017). doi.org/10.1515/jogs-2017-0008 - Phenotypic plasticity in tumor growth and dissemination
VOß-BöHME, Anja, 2016. Phenotypic plasticity in tumor growth and dissemination. eingeladener Vortrag, Workshop Modeling Tumor Evolution: Initiation, Growth and Progression, Zentrum für interdisziplinäre Forschung (ZiF) Bielefeld, September 2016. - Simulation sozioökonomischer Prozesse mit zellulären Automaten - räumliche Analyse des Kundenverhaltens konkurrierender Apotheken
Thomas Wiedemann, Anja Voß-Böhme, Marcel Stasik, 2016. Simulation sozioökonomischer Prozesse mit zellulären Automaten - räumliche Analyse des Kundenverhaltens konkurrierender Apotheken. T. Wiedemann (Hrsg.), Tagungsband ASIM 2016, 23. Simposium Simulationstechnik, ARGESIM Report 52, ASIM Mitteilung AM 160, ARGESIM Verlag Wien, 2016 . ISBN 978-3-901608-49-0 - The consequences of phenotypic plasticity on tumor growth and dissemination.
VOß-BöHME, Anja, 2016. The consequences of phenotypic plasticity on tumor growth and dissemination.. European Conference of Mathematical and Theoretical Biology, Nottingham, UK, July 11-16, 2016. - Model-Based Evaluation of Spontaneous Tumor Regression in Pilocytic Astrocytoma
BUDER, Thomas, DEUTSCH, Andreas, KLINK, Barbara, VOSS-BÖHME, Anja., 2015. Model-Based Evaluation of Spontaneous Tumor Regression in Pilocytic Astrocytoma. PLoS Computational Biology. doi: 10.1371/journal.pcbi.1004662 - Migration plasticity increases tumor cell dissemination
VOß-BöHME, Anja, 2015. Migration plasticity increases tumor cell dissemination. Workshop "Complex Methods in Biology", Turin (Italien), 5.-6.11.2015. - An Emerging Allee effect is critical for tumor initiation and persistance.
BÖTTGER, Katrin, HATZIKIROU, Haralambos, VOSS-BÖEHME, Anja, CAVALCANTI-ADAM, Ada, HERRERO, Miguel A., DEUTSCH, Andreas., 2015. An Emerging Allee effect is critical for tumor initiation and persistance.. PLOS Computational Biology 11(9):E1004366. Doi: 10.1371/journal.pcbi.1004366 - Analysis of individual cell trajectories in lattice-gas cellular automaton models for migrating cell populations.
MENTE, Carsten, VOSS-BÖHME, Anja, DEUTSCH, Andreas, 2015. Analysis of individual cell trajectories in lattice-gas cellular automaton models for migrating cell populations. . Bulletin of Mathematical Biology 77 (4), pp 660-697 (2015) . doi:10.1007/s11538-015-0079-3 - Challenges in modeling interacting and migrating cell populations.
Voß-Böhme, A., 2014. Challenges in modeling interacting and migrating cell populations.. Invited talk, Workshop Mathematical Models for Cancer Cell Migration, Mathematisches Forschungsinstitut Oberwolfach, April 2014. - How does a single cell know when the liver has reached its correct size?
HOHMANN, Nadine, WEIWEI, Wei., DAHMEN, Uta., DIRSCH, Olaf, DEUTSCH, Andreas, VOSS-BÖHME, Anja, 2014. How does a single cell know when the liver has reached its correct size? . PLoS ONE 9(4): e93207 (2014) . doi: 10.1371/journal.pone.0093207
20Erstellte Gutachten
- 1 Gutachten für ACRI 2014
Auftraggeber: Konferenz Cellular Automata for Research and Industry, Krakow, September 22-25, 2014 | Abgabedatum: 15.05.2014 - 1 Gutachten für Cancer Research
Auftraggeber: peer reviewed journal | Abgabedatum: 24.06.2015 - 1 Gutachten für Mathematical Biosciences
Auftraggeber: peer reviewed journal | Abgabedatum: 20.03.2020 - 1 Gutachten für Mathematical Reviews
Auftraggeber: Post-publication peer-review for Mathematical Reviews | Abgabedatum: 01.09.2015 - 1 Gutachten für Mathematical Reviews
Auftraggeber: post-publication peer review | Abgabedatum: 28.08.2015 - 1 Gutachten für Philosophical Transactions of the Royal Society B
Auftraggeber: peer-reviewed Journal | Abgabedatum: 25.11.2019 - 1 Gutachten für Philosophical Transactions of the Royal Society B
Auftraggeber: peer-reviewed Journal | Abgabedatum: 21.05.2020 - 1 Gutachten für Physical Review E
Auftraggeber: peer-reviewed journal | Abgabedatum: 08.04.2014 - 1 Gutachten für Physical Review E
Auftraggeber: peer-reviewed Journal | Abgabedatum: 30.04.2019 - 1 Gutachten für Physical Review Letters
Auftraggeber: peer reviewed journal | Abgabedatum: 26.07.2019 - 1 Gutachten für Physical Review Letters
Auftraggeber: peer-reviewed journal | Abgabedatum: 17.12.2014 - 1 Gutachten für Physical Review Letters
Auftraggeber: peer-reviewed journal | Abgabedatum: 18.07.2014 - 1 Gutachten für Physical Reviews E
Auftraggeber: peer reviewed journal | Abgabedatum: 13.01.2017 - 1 Gutachten für PLOS Computational Biology
Auftraggeber: peer-reviewed journal | Abgabedatum: 31.08.2017 - 1 Gutachten für PLOS Computational Biology
Auftraggeber: peer-revied journal | Abgabedatum: 08.11.2018 - 1 Gutachten für PLoS One
Auftraggeber: peer-reviewed journal | Abgabedatum: 30.10.2014 - 4 Gutachten für Mathematical Reviews
Auftraggeber: post publication reviews | Abgabedatum: 31.12.2014 - Gutachten für Physical Review E
Auftraggeber: peer-revied Journal | Abgabedatum: 12.08.2016 - Gutachten zur Dissertation "Construction and analysis of lattce-gas cellular automata models of collective migration" von Josue Manik Nava Sedeno
Auftraggeber: TU Dresden, Fakultät Mathematik | Abgabedatum: 14.06.2018 - Project review for a Call for Proposals in the field of multidisciplinary approaches in modeling complex biological processes applied to cancer field
Auftraggeber: Cancer TMOI of the French National Alliance for Life and Health Sciences (AVIESAN) jointly with the French National Cancer Institute (INCa) | Abgabedatum: 28.08.2017
4Betreute Promotionen (kooperativ)
- Impact of cell migration plasticity on tumor growth and invasion: cellular automaton modelling, simulation and analysis
Promovend: Dr. rer. nat. Katrin Talkenberger | Kooperierende Universität: Technische Universität Dresden | Status: abgeschlossen 2017 - Infering cellular mechanisms of tumor development from tissue-scale data: A Markov chain approach
Promovend: Dr. rer. nat. Thomas Buder | Kooperierende Universität: Technische Universität Dresden | Status: abgeschlossen 2018 - Mathematische Modellierung der Initiierung und Progression entarteter Gewebestrukturen
Promovend: M.Sc. Denis Hünniger | Kooperierende Universität: TU Dresden | Status: laufend - Modellierung und Vorhersage der multizellulären Gewebeorganisation mit Hilfe probabilistischer zellulärer Automaten
Promovend: M.Sc. Sebastian Rühle | Kooperierende Universität: Technische Universität Dresden | Status: laufend
3Mitarbeit in externen Gremien und Verbänden
- Editorial Board Member Journal Mathematical Biosciences
Seit: 01.08.2013 - European Society of Mathematical and Theoretical Biology (ESMTB)
Seit: 01.04.2010 - Fachgruppe Stochastik der Deutschen Mathematiker-Vereinigung
Seit: 01.01.2008
8Organisierte Fachveranstaltungen
- Minisymposium MS-13-AM-02 Cell-based models of tumor ecology and evolution
- Seminar in Mathematical Biology: Mathematics of Collective Cell Migration
- Seminar in Mathematical Biology: Mathematics of tumor evolution and ecology
- Seminar Mathematics of tumor progression
- Seminar Theories of cell aggregation and invasion
- Seminar Trends and Methods in Mathematical Biology
- SIMBA: Saxon Symposium on Informatics and Mathematics in Biological Applications
- Summer Solstice Conference on Discrete Models of Complex Systems 2019